Pig Kidney Xenotransplant Bridges Patient to Human Transplant

Patient survives 271 days on genetically edited pig kidney before receiving human organ.

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Andrews successfully lived with the genetically edited pig kidney for 271 days without needing dialysis before receiving a human kidney from a donor. ^[1] Tim Andrews, a 66-year-old patient with end-stage kidney disease, received a genetically edited pig kidney in January 2025 and subsequently received a human kidney in January 2026. ^[2] The 271 days Tim Andrews survived with the pig kidney set a new record for the duration of a xenotransplant, according to The Lancet. ^[3] Tim Andrews, a 66-year-old American man, survived nine months with a genetically modified pig kidney before receiving a human transplant. ^[4] Lead author Leonardo Riella, M.D., Ph.D., of Mass General Brigham stated that xenotransplantation could help address the organ shortage gap by initially serving as a bridge to get patients off dialysis while they wait for a human donor kidney. ^[5] This case represents the longest dialysis-free survival following porcine kidney xenotransplantation in a living human and the first transition to human kidney transplantation. ^[6] Irreversible damage to the kidney's blood vessels occurred after approximately six months, necessitating the removal of the organ after 271 days. ^[7] The pig kidney began producing urine within hours of the transplant but suffered a rejection episode two weeks later that was controlled with treatment. ^[8]

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Andrews successfully lived with the genetically edited pig kidney for 271 days without needing dialysis before receiving a human kidney from a donor. · Medical Xpress

Tim Andrews, a 66-year-old patient with end-stage kidney disease, received a genetically edited pig kidney in January 2025 and subsequently received a human kidney in January 2026. · Medical Xpress

The 271 days Tim Andrews survived with the pig kidney set a new record for the duration of a xenotransplant, according to The Lancet. · El Mundo

Tim Andrews, a 66-year-old American man, survived nine months with a genetically modified pig kidney before receiving a human transplant. · El Mundo

Lead author Leonardo Riella, M.D., Ph.D., of Mass General Brigham stated that xenotransplantation could help address the organ shortage gap by initially serving as a bridge to get patients off dialysis while they wait for a human donor kidney. · Medical Xpress

This case represents the longest dialysis-free survival following porcine kidney xenotransplantation in a living human and the first transition to human kidney transplantation. · Medical Xpress

Irreversible damage to the kidney's blood vessels occurred after approximately six months, necessitating the removal of the organ after 271 days. · El Mundo

The pig kidney began producing urine within hours of the transplant but suffered a rejection episode two weeks later that was controlled with treatment. · El Mundo

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