A study published in the journal PLOS Medicine concluded that spending long periods of time sitting without getting up can increase the risk of mortality from cancer. ^[1] According to the study authors, each additional hour of prolonged and uninterrupted sedentary behavior is associated with a 9% higher probability of dying from cancer. ^[2] Glasgow University researchers found that each additional half-hour of uninterrupted sitting increased cancer death risk by 9% in a study of UK Biobank data. ^[3] Replacing prolonged sedentary behavior with physical activity is associated with a lower risk of cancer death, according to the scientists' findings. ^[4] The study was led by Dr. Frederick Ho, an academic in Epidemiology and Statistics at the University of Glasgow in the United Kingdom. ^[5] Glasgow University researchers analyzed activity monitor records from more than 91,000 adults in the UK Biobank database over about 12 years. ^[6] The same Glasgow University study linked prolonged uninterrupted sitting directly to six cancer types: liver, kidney, pancreas, colon, breast, and thyroid. ^[7] The study found that replacing one hour of daily sitting with light physical activity reduced cancer death risk by 12%. ^[8]