Compared with White women residing in similar social vulnerability index (SVI) areas, Black women in both low- and high-SVI areas had significantly greater hazards of death, with adjusted hazard ratios of 1.20 and 1.60, respectively. [1][3]
Researchers identified activating mutations in the CSF1R gene and additional receptor tyrosine kinases in patients with histiocytic neoplasms. [2] Francesmary Modugno, Ph.D., M.P.H., from the University of Pittsburgh School of Medicine, and colleagues found that Black women in the study had a higher likelihood than White women of being diagnosed with epithelial ovarian cancer at a more advanced stage (68.0% versus 62.6%). [4] Benjamin H. Durham and Estibaliz Lopez Rodrigo contributed equally to the study on histiocytic neoplasms. [5]
Collaborators included researchers from the University of Pittsburgh School of Medicine, Ghent University in Belgium, and Hospital Sant Joan de Déu in Barcelona. [6] The research involved contributions from departments of medicine, pathology, pediatrics, immunology, and ophthalmic oncology. [7]En comparación con las mujeres blancas que residen en áreas con un índice de vulnerabilidad social (SVI) similar, las mujeres negras en áreas de SVI bajo y alto tuvieron riesgos de muerte significativamente mayores, con razones de riesgo ajustadas de 1,20 y 1,60, respectivamente. [1][3]
Los investigadores identificaron mutaciones activadoras en el gen CSF1R y otros receptores de tirosina quinasa en pacientes con neoplasias histiocíticas. [2] Francesmary Modugno, Ph.D., M.P.H., de la Facultad de Medicina de la Universidad de Pittsburgh, y sus colegas encontraron que las mujeres negras en el estudio tenían una mayor probabilidad que las mujeres blancas de ser diagnosticadas con cáncer de ovario epitelial en una etapa más avanzada (68,0% frente a 62,6%). [4] Benjamin H. Durham y Estibaliz Lopez Rodrigo contribuyeron por igual al estudio sobre neoplasias histiocíticas. [5]
Entre los colaboradores se incluyeron investigadores de la Facultad de Medicina de la Universidad de Pittsburgh, la Universidad de Gante en Bélgica y el Hospital Sant Joan de Déu en Barcelona. [6] La investigación contó con contribuciones de los departamentos de medicina, patología, pediatría, inmunología y oncología oftálmica. [7]
Proof7 sources · 2 publishers
What this stands on
The study associated living in areas of greater social vulnerability with worse overall survival (adjusted hazard ratio 1.20), with a significantly stronger effect for Black women (adjusted hazard ratio 1.77) than White women (adjusted hazard ratio 1.10). · Medical Xpress
Researchers identified activating mutations in the CSF1R gene and additional receptor tyrosine kinases in patients with histiocytic neoplasms. · Nature
Compared with White women residing in similar social vulnerability index (SVI) areas, Black women in both low- and high-SVI areas had significantly greater hazards of death, with adjusted hazard ratios of 1.20 and 1.60, respectively. · Medical Xpress
Francesmary Modugno, Ph.D., M.P.H., from the University of Pittsburgh School of Medicine, and colleagues found that Black women in the study had a higher likelihood than White women of being diagnosed with epithelial ovarian cancer at a more advanced stage (68.0% versus 62.6%). · Medical Xpress
Benjamin H. Durham and Estibaliz Lopez Rodrigo contributed equally to the study on histiocytic neoplasms. · Nature
Collaborators included researchers from the University of Pittsburgh School of Medicine, Ghent University in Belgium, and Hospital Sant Joan de Déu in Barcelona. · Nature
The research involved contributions from departments of medicine, pathology, pediatrics, immunology, and ophthalmic oncology. · Nature
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