Neighborhood vulnerability affects ovarian cancer survival more for Black women

Study of 2,544 women shows social vulnerability affects ovarian cancer survival more for Black women than White women.

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The study associated living in areas of greater social vulnerability with worse overall survival (adjusted hazard ratio 1.20), with a significantly stronger effect for Black women (adjusted hazard ratio 1.77) than White women (adjusted hazard ratio 1.10). ^[1] Researchers identified activating mutations in the CSF1R gene and additional receptor tyrosine kinases in patients with histiocytic neoplasms. ^[2] Compared with White women residing in similar social vulnerability index (SVI) areas, Black women in both low- and high-SVI areas had significantly greater hazards of death, with adjusted hazard ratios of 1.20 and 1.60, respectively. ^[3] Francesmary Modugno, Ph.D., M.P.H., from the University of Pittsburgh School of Medicine, and colleagues found that Black women in the study had a higher likelihood than White women of being diagnosed with epithelial ovarian cancer at a more advanced stage (68.0% versus 62.6%). ^[4] Benjamin H. Durham and Estibaliz Lopez Rodrigo contributed equally to the study on histiocytic neoplasms. ^[5] Collaborators included researchers from the University of Pittsburgh School of Medicine, Ghent University in Belgium, and Hospital Sant Joan de Déu in Barcelona. ^[6] The research involved contributions from departments of medicine, pathology, pediatrics, immunology, and ophthalmic oncology. ^[7]

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Researchers identified activating mutations in the CSF1R gene and additional receptor tyrosine kinases in patients with histiocytic neoplasms. · Nature

Compared with White women residing in similar social vulnerability index (SVI) areas, Black women in both low- and high-SVI areas had significantly greater hazards of death, with adjusted hazard ratios of 1.20 and 1.60, respectively. · Medical Xpress

Francesmary Modugno, Ph.D., M.P.H., from the University of Pittsburgh School of Medicine, and colleagues found that Black women in the study had a higher likelihood than White women of being diagnosed with epithelial ovarian cancer at a more advanced stage (68.0% versus 62.6%). · Medical Xpress

Benjamin H. Durham and Estibaliz Lopez Rodrigo contributed equally to the study on histiocytic neoplasms. · Nature

Collaborators included researchers from the University of Pittsburgh School of Medicine, Ghent University in Belgium, and Hospital Sant Joan de Déu in Barcelona. · Nature

The research involved contributions from departments of medicine, pathology, pediatrics, immunology, and ophthalmic oncology. · Nature

We could not place any of them by their address. None is an official body: that part stands on reporting, not on the underlying document or transcript.

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