A study published in Communications Medicine analyzed data from 104,806 participants in the NutriNet-santé e-cohort study to investigate the relationship between eating jetlag and cardiovascular disease risk. ^[1] The study found a significant association between eating jetlag and increased risks of cardiovascular disease and coronary heart disease among male participants over a median follow-up of 8.1 years. ^[2] For men, every additional hour of difference between weekday and weekend meal times was associated with a 14 percent increase in the risk of cardiovascular disease. ^[3] Researchers published a study in the journal Communications Medicine stating that shifting usual meal times on weekends is associated with an increased risk of cardiovascular disease in men. ^[4] Men in the 'advance' group, who ate more than one hour earlier on weekends than on weekdays, showed significant associations with increased risks of cardiovascular disease and coronary heart disease compared to the maintenance group. ^[5] The study detected significant associations in men but not in women, although the formal test for a sex-by-sex interaction was not statistically significant. ^[6] For men, every additional hour of difference in meal times was associated with a 21 percent increase in the risk of ischemic heart disease. ^[7] Researchers compared the timing of the first and last meals of participants on weekdays versus weekends, while accounting for age, smoking, alcohol consumption, physical activity, diet, sleep duration, and other factors. ^[8]